Please use this identifier to cite or link to this item: http://hdl.handle.net/11717/2555
Title: Determination of isoniazid in pharmaceutical preparations by reaction with radiochloramine-B
Authors: Subhashini, M.
Subramanian, M.S.
Rao, V.R.S.
Keywords: aminosalicylic acid
ascorbic acid
chloramine b
isokin
isoniazid
rifampicin
unclassified drug
conference paper
drug determination
drug mixture
methodology
nonhuman
oxidation
Ascorbic Acid
Chloramines
Indicators and Reagents
Isoniazid
p-Aminosalicylic Acid
Rifampin
Support, Non-U.S. Gov't
Issue Date: 1989
Citation: Journal of Pharmaceutical and Biomedical Analysis, 7(12), 1473-1477
Abstract: A method has been developed for the determination of isoniazid (INH) at microgram level in pharmaceutical preparations based on the oxidation of isoniazid by radiochloramine-B. Interference of vitamin C has been overcome by precipitation as lead ascorbate and that of rifampicin and p-aminosalicylic acid by selective extraction. Amounts as low as 25 ?g of INH can be determined. ? 1990.
URI: http://dx.doi.org/10.1016/0731-7085(89)80153-0
http://hdl.handle.net/11717/2555
ISSN: 7317085
Appears in Collections:Articles

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