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|Title:||Determination of isoniazid in pharmaceutical preparations by reaction with radiochloramine-B|
Indicators and Reagents
Support, Non-U.S. Gov't
|Citation:||Journal of Pharmaceutical and Biomedical Analysis, 7(12), 1473-1477|
|Abstract:||A method has been developed for the determination of isoniazid (INH) at microgram level in pharmaceutical preparations based on the oxidation of isoniazid by radiochloramine-B. Interference of vitamin C has been overcome by precipitation as lead ascorbate and that of rifampicin and p-aminosalicylic acid by selective extraction. Amounts as low as 25 ?g of INH can be determined. ? 1990.|
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