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Deepak Khemani
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Deepak Khemani
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Deepak Khemani
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KHEMANI, D. E.E.P.A.K.
Khemani, Deepak
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3 results
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- PublicationArtificial Intelligence: The Age-old Quest for Thinking Machines(01-01-2020)The phrase artificial intelligence has become common in our current day discourse. Fuelled by successes in machine learning, and applications interacting with us in speech and natural language, many commentators have made a leap of faith that behind these successes is a thinking machine, and this has even stoked fears of machines overcoming humankind. In this two-part article, we look at how close we are to the original quest for creating “machines who think”. In the first part, we trace the evolution of mechanical computers and also the notion of the mind up to the era before digital computers appeared on the horizon.
- PublicationArtificial Intelligence: The Big Picture(01-01-2020)In the first week of the year 2020, we got the news that AI now outperforms doctors in detecting breast cancer. This is in line with a continuous stream of news coming from the world of diagnosis and has lent credence to the sentiment that AI is poised to overcome humankind. However, some perceptive observers have commented that recent advances are largely due to the massive increase in both availability of data and computing power. Moreover, it is only a narrow task of classification that has led the news blitz. Classification can be thought of as a stimulus-response process. Human intelligence is much broader. In particular, humans often display a stimulus-deliberation-response cycle. There is much that goes on in the “thinking” phase that was the original aim of AI before the data and speed started dominating applications. The second of the two-part article on AI traces the evolution in the field since the Dartmouth conference, and takes stock of where we are on the road to thinking machines.
- PublicationUnveiling the versatility of gelatin methacryloyl hydrogels: a comprehensive journey into biomedical applications(2024-07-01)
;Pramanik, Sheersha ;Alhomrani, Majid ;Alamri, Abdulhakeem S. ;Alsanie, Walaa F. ;Nainwal, Pankaj ;Kimothi, Vishwadeepak; Sargsyan, Armen S.Gelatin methacryloyl (GelMA) hydrogels have gained significant recognition as versatile biomaterials in the biomedical domain. GelMA hydrogels emulate vital characteristics of the innate extracellular matrix by integrating cell-adhering and matrix metalloproteinase-responsive peptide motifs. These features enable cellular proliferation and spreading within GelMA-based hydrogel scaffolds. Moreover, GelMA displays flexibility in processing, as it experiences crosslinking when exposed to light irradiation, supporting the development of hydrogels with adjustable mechanical characteristics. The drug delivery landscape has been reshaped by GelMA hydrogels, offering a favorable platform for the controlled and sustained release of therapeutic actives. The tunable physicochemical characteristics of GelMA enable precise modulation of the kinetics of drug release, ensuring optimal therapeutic effectiveness. In tissue engineering, GelMA hydrogels perform an essential role in the design of the scaffold, providing a biomimetic environment conducive to cell adhesion, proliferation, and differentiation. Incorporating GelMA in three-dimensional printing further improves its applicability in drug delivery and developing complicated tissue constructs with spatial precision. Wound healing applications showcase GelMA hydrogels as bioactive dressings, fostering a conducive microenvironment for tissue regeneration. The inherent biocompatibility and tunable mechanical characteristics of GelMA provide its efficiency in the closure of wounds and tissue repair. GelMA hydrogels stand at the forefront of biomedical innovation, offering a versatile platform for addressing diverse challenges in drug delivery, tissue engineering, and wound healing. This review provides a comprehensive overview, fostering an in-depth understanding of GelMA hydrogel’s potential impact on progressing biomedical sciences.