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Venkitasamy Kesavan
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Preferred name
Venkitasamy Kesavan
Official Name
Venkitasamy Kesavan
Alternative Name
Kesavan, Venkitasamay
Venkitasamy, Kesavan
Kesavan, Venkitasamy
Kesavan, Ventikasamy
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2 results
Now showing 1 - 2 of 2
- PublicationOrganocatalytic Enantioselective Assembly of Spirooxindole-naphthopyrans through Tandem Friedel-Crafts Type/Hemiketalization(09-05-2016)
;Muthusamy, Subramaniam ;Prakash, Muthuraj ;Ramakrishnan, Chandrasekaran; A new synthetic strategy to construct spirooxindole-naphthopyran scaffold has been demonstrated via Friedel-Crafts type/hemiketalization of oxindole α-ketoester with 2-naphthol. Under the established reaction condition, quaternary chiral center at C3-position of oxindole has been created with very good asymmetric induction up to 98 % for a broad range of substrates. DFT calculations, which account for the stereochemical outcome, were performed. - PublicationConstruction of Polycyclic Fused Pyrrolidines with Three Contiguous Stereocenters via Michael Addition of Vinylmalononitriles to Nitrostyrenes Using l -Proline-Derived Thiourea(16-08-2016)
;Vishwanath, Manjunatha ;Prakash, Muthuraj ;Vinayagam, PoopathyThe catalytic efficiency of a bifunctional chiral thiourea derived from l-proline was evaluated in the asymmetric direct vinylogous Michael reaction of α,α-dicyanoolefins to β-nitrostyrenes with an electron-releasing or electron-withdrawing substituent in various positions. The corresponding adducts were isolated in good yields, with excellent diastereo- (>99%) and enantioselectivity (up to 95%). The Michael adducts were further functionalized to achieve the synthesis of polycyclic fused pyrrolidines with three contiguous stereocenters in good enantioselectivities.