Now showing 1 - 2 of 2
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    Publication
    Constriction based microfluidic device for the cell phenotyping
    (01-01-2016)
    Raj, A.
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    We report a constriction based microfluidic device for characterization of mechanical properties of single cells. The device is capable of measuring the effect of size ratio, entry angle as well as external pressure applied across the constrictions on cell movement. Multiple cells can be processed through the constrictions at a single stretch. The device can give much higher throughput than the single constriction device normally used for all the experiments. It was observed, the entry time increase with the decrease in the cone angle (entry angle). Experimentally, the velocity of the cell was found to increase along the constriction length.
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    Publication
    Fast frame rate rodent cardiac x-ray imaging using scintillator lens coupled to CMOS camera
    (01-01-2017)
    Swathi Lakshmi, B.
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    Sai Varsha, M. K.N.
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    Kumar, Ashwin N.
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    Micro-Computed Tomography (MCT) systems for small animal imaging plays a critical role for monitoring disease progression and therapy evaluation. In this work, an in-house built micro-CT system equipped with a X-ray scintillator lens coupled to a commercial CMOS camera was used to test the feasibility of its application to Digital Subtraction Angiography (DSA). Literature has reported such studies being done with clinical X-ray tubes that can be pulsed rapidly or with rotating gantry systems, thus increasing the cost and infrastructural requirements.The feasibility of DSA was evaluated by injected Iodinated contrast agent (ICA) through the tail vein of a mouse. Projection images of the heart were acquired pre and post contrast using the high frame rate X-ray detector and processing done to visualize transit of ICA through the heart.