Options
Saumendra K Bajpai
Loading...
Preferred name
Saumendra K Bajpai
Official Name
Saumendra K Bajpai
Alternative Name
Bajpai, Saumendra Kumar
Bajpai, Saumendra
Bajpai, Saumendra K.
Main Affiliation
Email
ORCID
Scopus Author ID
Google Scholar ID
2 results
Now showing 1 - 2 of 2
- PublicationThermodynamically-consistent constitutive modeling of aligned Silk fibroin sponges: Theory and application to uniaxial compression(01-05-2018)
;Panda, Debojyoti ;Konar, Subhajit; Arockiarajan, A.Microstructurally-aligned Silk fibroin sponges have emerged as a viable candidate for replicating the anisotropic fibrous microarchitecture that is encountered in several functional tissues in vivo. But for the material to reach its full potential in terms of its application in biomimetic soft tissue constructs or scaffolds, a complete understanding and quantification of its nonlinear viscoelastic response in the finite strain regime is needed. To address this gap from the mechanical modeling perspective, an anisotropic, nonlinear, viscoelastic model is developed within a thermodynamic framework in this study, to capture the macroscopic response of these sponges in a phenomenological manner. The rate-type constitutive equations that are developed in the process are subsequently applied for the case of uniaxial compression, and satisfactorily corroborated against the results from finite strain viscoelastic characterization experiments done on hydrated Silk fibroin sponges under uniaxial compression for different constituent material concentrations of the sponges ranging from 1 w/v % - 4 w/v %. - PublicationSynthesis and viscoelastic characterization of microstructurally aligned Silk fibroin sponges(01-07-2017)
;Panda, Debojyoti ;Konar, Subhajit; Arockiarajan, A.Silk fibroin (SF) is a model candidate for use in tissue engineering and regenerative medicine owing to its bio-compatible mechanochemical properties. Despite numerous advances made in the fabrication of various biomimetic substrates using SF, relatively few clinical applications have been designed, primarily due to the lack of complete understanding of its constitutive properties. Here we fabricate microstructurally aligned SF sponge using the unidirectional freezing technique wherein a novel solvent-processing technique involving Acetic acid is employed, which obviates the post-treatment of the sponges to induce their water-stability. Subsequently, we quantify the anisotropic, viscoelastic response of the bulk SF sponge samples by performing a series of mechanical tests under uniaxial compression over a wide range of strain rates. Results for these uniaxial compression tests in the finite strain regime through ramp strain and ramp-relaxation loading histories applied over two orders of strain rate magnitude show that microstructural anisotropy is directly manifested in the bulk viscoelastic solid-like response. Furthermore, the experiments reveal a high degree of volume compressibility of the sponges during deformation, and also evince for their remarkable strain recovery capacity under large compressive strains during strain recovery tests. Finally, in order to predict the bulk viscoelastic material properties of the fabricated and pre-characterized SF sponges, a finite strain kinematics-based, nonlinear, continuum model developed within a thermodynamically-consistent framework in a parallel investigation, was successfully employed to capture the viscoelastic solid-like, transversely isotropic, and compressible response of the sponges macroscopically.