Electrochemical Sensing of Anesthetics using Polythiophene Coated Glassy Carbon Electrodes

A novel electrochemical sensor for anesthetics employing the polymerization of Thiophene onto glassy carbon electrodes is demonstrated. The polymer was characterized by electrochemical and morphological characterizations using cyclic voltammetry, differential pulse voltammetry, Fourier transform infrared spectroscopy and scanning electron microscopy. This polythiophene modified electrode was employed for sensing anesthetics and a lowest detection limit of 35 nM, 50 nM and 20 nM were obtained for Procaine, Benzocaine and Procainamide respectively. The interference studies showed the selectivity of this electrode in the presence of common interfering agents. The Dopaminergic effect of Procaine is studied by varying concentrations of dopamine and a thorough study established the profound effect.