Publication:
Halogenative kinetic resolution of β-amido alcohols: Chiral BINAP-mediated S<inf>N</inf>2 displacement of hydroxy groups by chlorides with inversion of stereochemistry

cris.author.scopus-author-id15848148800
cris.author.scopus-author-id6602184820
cris.virtual.author-orcid0000-0003-2294-0485
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.departmentIndian Institute of Technology, Madras
cris.virtual.department#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcida77c338c-b73c-4dcc-89ee-e0affae516e5
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.departmenta77c338c-b73c-4dcc-89ee-e0affae516e5
cris.virtualsource.department#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.contributor.authorJaseer, E. A.
dc.contributor.authorG Sekar
dc.date.accessioned2023-09-20T05:25:32Z
dc.date.available2023-09-20T05:25:32Z
dc.date.issued21-04-2010
dc.description.abstractA series of optically active cyclic trans-β-amido alcohols were obtained by the non-enzymatic kinetic resolution of the corresponding racemic amido alcohols using commercially available (S)-BINAP and NCS by SN2 halogenation of the hydroxy group. The product, cis-β-amido chloride, was also obtained in optically active form with an inversion of stereochemistry. © 2010 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.tetasy.2010.04.011
dc.identifier.issn9574166
dc.identifier.scopus2-s2.0-77956189284
dc.identifier.urihttps://apicris.irins.org/handle/IITM2023/44095
dc.relation.ispartofseriesTetrahedron Asymmetry
dc.sourceTetrahedron Asymmetry
dc.titleHalogenative kinetic resolution of β-amido alcohols: Chiral BINAP-mediated S<inf>N</inf>2 displacement of hydroxy groups by chlorides with inversion of stereochemistry
dc.typeJournal
dspace.entity.typePublication
oaire.citation.endPage785
oaire.citation.issue7
oaire.citation.startPage780
oaire.citation.volume21
oairecerif.author.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#
oairecerif.author.affiliationIndian Institute of Technology, Madras
person.affiliation.cityChennai
person.affiliation.id60025757
person.affiliation.nameIndian Institute of Technology Madras
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