Options
2-O-benzylation in D-gluconamide derivative under basic conditions with complete retention of stereo-integrity: Convenient access to 2-O-benzyl-3,4:5,6-di-O-isopropylidene-D-glucitol and other differently protected D-glucitol derivatives
Date Issued
01-07-2009
Author(s)
Manjunath, B. N.
Harikrishna, K.
Indian Institute of Technology, Madras
Varghese, B.
Abstract
A new and convenient synthesis of 2-O-benzyl-3, 4: 5, 6-di-O- isopropylidene-D-glucitol has been accomplished and has been generalized with the syntheses of differently protected D-glucitols at C-2 position. In the course of our new route to the differently protected D-glucitols at C-2 position, a new D-gluco configured building block, 1-morpholino-(3, 4: 5, 6-di-O-isopropylidene)-D-gluconamide has been achieved.
Volume
28