Numerical modeling of drug delivery to posterior segment of eye

Intravitreous injection and transscleral drug delivery are numerically modeled in the present study. Two dimensional computational domain, generated with the actual eye geometry, is used for simulation. Laser heated vitrectomized eye showed better drug transport to the retinal region. For a centrally injected drug, the convection assisted diffusion transported drug in 30 minutes to the retinal region as compared to the 2.7 hours for the pure diffusion case. Also transscleral drug transport of direct injection route and from implant, has been simulated and preliminary results are presented.