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27th Annual CSP Workshops on "Recent Developments in Computer Simulation Studies in Condensed Matter Physics", CSP 2014 A computational study of blebbing in lipid membranes
Date Issued
01-01-2014
Author(s)
Abstract
Blebs are membrane protrusions that appear during several physiological processes in eukaryotic cells. The phase behavior and kinetics of blebbing in cellular membrane is investigated computationally using a particle-based model for self-assembled lipid vesicles apposed to an elastic meshwork, mimicking a cell's cytoskeleton. We found that blebbing is induced when the cytoskeleton is subjected to a localized ablation, detachment from the membrane, or a uniform contraction. These results are in good agreement with experiments.
Volume
57