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Tea polyphenols stimulate mt bioenergetics in cardiometabolic diseases
Date Issued
01-01-2023
Author(s)
Srividhya, Ravichandran
Abstract
Cardiometabolic diseases are a category of noncommunicable diseases related to changes in lifestyle. Noncommunicable diseases have been called a global emergency in the rising arena of the academic and political community. Cardiovascular diseases (CVDs) are considered to be one of the leading causes of death worldwide, with >80% CVD-related deaths in low- and middle-income countries. Metabolic syndrome refers to a cluster of pathological conditions that provoke a major risk for CVD and other metabolically-associated syndromes like Type II Diabetes mellitus and has also emerged as a major health problem in the modern society, associated with enormous social, personal, and economic burden in both the developing and developed countries of the world. Literature cites that genetic defects are implicated in many cardiometabolic diseases. Metabolic syndromes have an associated cardiovascular risk by 50%–60% higher than people who do not possess any. Cardiovascular risks associated with metabolic syndrome includes the involvement of factors like genetic disposition, obesity, insulin resistance, and inflammation. The counteractive effects of phytochemicals which are found in plants have been in the limelight for many years. Tea polyphenols which are rich in antioxidants render protection against metabolic diseases associated with the heart. This review summarises the cytoprotective actions of tea polyphenols in cardiometabolic disorders.