Electrochemical activity of 3D hairy hollow sphered Mn-Cu-Al layered hydroxide nanocomposites: A short survey on glucose analyte

A sensitive hollow shell-based non-enzymatic glucose sensor was developed using Mn-Cu-Al layered triple hydroxide on the surface of nickel foam (Mn-Cu-Al-TH/NF). Mn-Cu-Al-TH nanocomposites were prepared using a facile microwave-assisted technique, and its hollow structure was created by continuous treatment with urea. The electrochemical activity of the Mn-Cu-Al-TH/NF electrode was examined by cyclic voltammetric techniques. It was identified that the Mn-Cu-Al-TH/NF electrode exhibited enhanced electrocatalytic activity towards glucose oxidation in alkaline medium (pH = 13), as compared with Mn-Cu-DH/NF and Mn-H/NF electrodes. The electrocatalytic activity of the modified electrode under various pH values has been investigated. Under the optimized conditions, the electrochemical sensor exhibits a linear sensitivity towards glucose from 5 μM to 4 mM with a sensitivity of 2,108 μA mM−1 cm−2. Moreover, the glucose sensor demonstrated good selectivity, stability, fast response (<2 s), and repeatability. Our results suggest that Mn-Cu-Al-TH hollow-shelled layered triple hydroxide (LTH) nanocomposite could be a promising candidate for the construction of a nonenzymatic sensor.