Simple synthetic equivalents for the beta-(N,N-disubstituted)ethylamino acyl cation synthon and their applications

Various N,N-disubstituted-beta -amino-N-methoxy-N-methylpropanamides 3a-i were prepared which served as an excellent beta -aminoacyl cation equivalents. These were used to prepare beta -amino ketones 1, pharmacological ly active tertiary 1-(3,3-diarylpropyl)amines 7a-c. and the interesting C-glycoside 8.