1,2,3-triazolophanes-cyclophanes with an array of molecular structures and supramolecular architectures

1,2,3-Triazolophanes are a class of cyclophanes that has attracted enormous attention in recent times. With the advent of the intramolecular copper-mediated alkyne azide cycloaddition (CuAAC) reaction 1,2,3-triazolophanes of various molecular structure and supramolecular architecture have been synthesized. 1,2,3-Triazolophanes find a variety of applications as molecular hosts, ion sensors, peptidomimics, and supramolecular building blocks, among others. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.