High resolution MR image of brain with signal attenuation of gray matter

A novel MR image acquisition protocol has been presented in order to obtain high resolution image of the brain at acquisition time. For better delineation of the substructures of the brain we have emphasized enhancing the intensity difference between white and gray matters in the reconstructed MR image of the brain. The mathematical basis of the protocol stems from the T1 weighting combined with an attempt of exploitation of the signal nulling effect. The protocol has been finalized for 1.5 tesla field strength and tested with multiple subjects. The results consistently show brilliant contrast between white and gray matters. These images are further evaluated subjectively as well as objectively to test the potentiality of the protocol to produce high contrast images over the conventional acquisition protocol. © 2010 IEEE.