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Bone-like structure by modified freeze casting

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cris.virtual.department#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.departmentIndian Institute of Technology, Madras
cris.virtualsource.department#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.department2508a983-7db3-452e-afbf-50da6f7fe15e
dc.contributor.authorSingh, Gurdev
dc.contributor.authorSoundarapandian, S.
dc.date.accessioned2023-09-19T13:34:52Z
dc.date.available2023-09-19T13:34:52Z
dc.date.issued01-12-2020
dc.description.abstractFreeze casting has emerged as one of the most promising manufacturing methods to fabricate porous scaffolds in recent years. This is due to various reasons which include a wide range of materials which can be used in this process, easiness of the process, etc. One of the major objectives of this work was to fabricate bone-like structure by using a modified freeze casting process. In this work, Hydroxyapatite and Tricalcium phosphate scaffolds with bone-like structure were fabricated by understanding and utilizing the basic physics of freeze casting. Thermal conductivity of the base plate is a crucial factor for obtaining controlled pore and porosity distribution in a porous scaffold. It was found that designing the base plate with variable thermal conductivity has led to the formation of bone-like structure. Porous scaffolds were quantitatively analyzed for pore size and porosity distribution at center and circumference. Porosity at circumference was observed to be approximately dropped by 55%, a similar trend was seen for pore size. Therefore, it was significant evidence that modified freeze casting has capable in fabricating bone-like structures with ease and good control. This will open many new applications of porous scaffolds in biomedical, energy devices, chemical catalyst and many more.
dc.identifier.doi10.1038/s41598-020-64757-z
dc.identifier.pmid32404933
dc.identifier.scopus2-s2.0-85084626194
dc.identifier.urihttps://apicris.irins.org/handle/IITM2023/21318
dc.relation.ispartofseriesScientific Reports
dc.sourceScientific Reports
dc.titleBone-like structure by modified freeze casting
dc.typeJournal
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.volume10
oairecerif.author.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#
oairecerif.author.affiliationIndian Institute of Technology, Madras
person.affiliation.cityChennai
person.affiliation.id60025757
person.affiliation.nameIndian Institute of Technology Madras
person.identifier.scopus-author-id57203792822
person.identifier.scopus-author-id34877656100
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