An intramolecular Schmidt reaction strategy for the synthesis of a methyl analogue of crispine A

Kumar, Ponminor Senthil; Kapat, Ajoy; Sundarababu Baskaran

doi:10.1016/j.tetlet.2007.12.040

An intramolecular Schmidt reaction strategy for the synthesis of a methyl analogue of crispine A

Date Issued

11-02-2008

Author(s)

Kumar, Ponminor Senthil

Kapat, Ajoy

Sundarababu Baskaran

Indian Institute of Technology, Madras

DOI

10.1016/j.tetlet.2007.12.040

Abstract

A convenient approach for the synthesis of a methyl analogue of crispine A, a potent anticancer agent, through intramolecular Schmidt reaction of azido-ketone 6 is described. © 2007 Elsevier Ltd. All rights reserved.

Volume

49

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An intramolecular Schmidt reaction strategy for the synthesis of a methyl analogue of crispine A