Structure analysis of methyl-3,4-dihydro-3-(p-methylphenyl)-4-oxo-2-quinazolinyl thiopropionate

The crystal structure of methyl-3, 4-dihydro-3-(p-methylphenyl)-4-oxo-2-quinazolinyl thiopropionate (C19H18N2O3S) has been determined by X-ray diffraction methods. The compound crystallizes in the triclinic space group PI with unit cell parameters: a = 9.094(2), b = 9.428(3), c = 10.612(3) Å, α 94.55(3), β = 95.44(2), γ = 106.75(3)° and Z = 2. The structure has been refined to an R-value of 0.054 for 2533 observed reflections [Fo>4σ(Fo)]. The quinazoline moiety and the methyl substituted phenyl ring is almost planar. The dihedral angle between these two moieties is 84.96(8)°. The crystal structure is stabilized by an intermolecular C-H...O interaction.