Asymmetric Organocatalytic Assembly of Oxindoles Fused with Spiro-3,4-dihydropyrans with Three Contiguous Stereocenters Consisting of Vicinal Quaternary Centers

Date Issued
01-05-2016
Author(s)
Vishwanath, Manjunatha
Vinayagam, Poopathy
Gajulapalli, V. Pratap Reddy
Indian Institute of Technology, Madras
DOI
Abstract
Diverse bispiro-3,4-dihydropyrans consisting of oxindole moieties with three contiguous chiral centers and vicinal quaternary stereocenters were synthesized with very good yields of up to 92% and excellent enantioselectivity of up to 99% ee by using a proline-derived thiourea organocatalyst.
Volume
5
Subjects