Publication: Ring-opening reactions of epoxides catalyzed by molybdenum(VI) dichloride dioxide
Date
03-03-2008
Authors
Dillip Kumar Chand
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Transformation of epoxides to β-alkoxy alcohols, acetonides, and α-alkoxy ketones is achieved by using molybdenum(VI) dichloride dioxide (MoO2Cl2) as a catalyst. Alcohol, aldehyde, oxime, tosyl, and tert-butyldimethylsilyl functional groups are tolerated during the methanolysis and acetonidation of the functionalized epoxides. No polymerization product is observed with any of the epoxides. Direct conversion of epoxides devoid of sensitive functional groups into the corresponding α-methoxy ketone is achieved in a single step by using the MoO2Cl 2/Oxone system. © Georg Thieme Verlag Stuttgart.
Description
Keywords
Catalyst, Epoxides, Molybdenum, Nucleophiles, Ring opening