Action of (2→1)fructo-oligopolysaccharide fraction of Chlorophytum borivilianum against streptozotocin-induced oxidative stress

A fructo-oligosaccharide was isolated from Chlorophytum borivilianum and identified as O-β-D-fructofuranosyl-(2→1)-(β-D-fructofuranosyl) n-(2→1)-α-D-glucopyranoside (n = 5-30) using high-pressure anion exchange chromatography, MALDI-MS, NMR, GC, HPTLC and chemical analysis. The extract and the fructo-oligosaccharide were found to have significant antidiabetic activity with the blood sugar levels being 118.32 ± 3.56 and 110.21 ± 4.22, respectively, as compared to the control value of 231.25 ± 3.03 along with moderate antioxidant activity in streptozotocin-induced diabetic animals. © George Thieme Verlag KG Stuttgart.