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A convenient and simple method for the synthesis of condensed γ-lactams and substituted xanthones from cyclic-1,3-diketones
Date Issued
04-08-2000
Author(s)
Chandrasekhar, B.
Ramadas, S. R.
Ramana, D. V.
Abstract
A systematic study of alkylation of cyclic-1,3-diones with 2-bromo-6-methoxybenzofuran-3-one was undertaken. Upon condensation in acetic acid with p-substituted aniline the O-alkylated product 3a gave condensed γ-lactam heterocycle 4. In contrast, the condensation of analogous O-alkylated derivatives 3b and 3c with p-substituted anilines furnished the substituted xanthone derivatives 6 and 7a. The probable mechanism of formation of 4, 6 and 7a was discussed. (C) 2000 Elsevier Science Ltd.
Volume
56