Determination of the partition coefficient of 1-naphthol, an excited state acid, in DMPC membrane

1-Naphthol, an excited state acid, undergoes partial dissociation in the excited state in liposome membranes, giving rise to two peaks, as opposed to a single peak in water. The excited state prototropic equilibrium is affected by perturbations in the membrane system. This property can be used to probe the properties of biomembranes. In this respect, as a preliminary study, the partition coefficient of 1-naphthol in liposomes has been calculated.