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Flow-Assisted Degradation of Magnesium Implant Pins Under Simulated Body Fluids and Goat Blood Plasma Environment
Date Issued
01-03-2022
Author(s)
Srinidhi, P. H.
Manne, Bhaskar
Prakrathi, S.
Abstract
Magnesium alloys have been finding their importance as biodegradable implants. Understanding the effects of fluid chemistry and flow conditions is essential for the better applicability of non-load bearing magnesium implants. This study focuses on in vitro flow-assisted biodegradation under three different fluids namely, Hank’s balanced salt solution (HBSS), HBSS plus minute addition of goat serum albumin (GSA) and a biological fluid: goat blood plasma (GBP). The chemical complexity of the fluids has an impact on the morphology of corrosion products. The corrosion rates found to increase with both complexities of the fluid chemistry and flow rates. Lowest corrosion rate (0.15 mm/year) was observed in the samples exposed to HBSS at 1 mL/min and the highest corrosion rate (17.6 mm/year) was observed in the samples exposed to GBP at higher flow rate of 3 mL/min. A minute addition (10 mg/L) of GSA to HBSS also shows a noticeable increase in the corrosion rate in lower flow rates 1 and 2 mL/min.
Volume
8