Dehydrogenative Cross-Coupling of α,β-Unsaturated Compounds with Unactivated Olefins via Co(III) Catalysis

An oxidative cross-coupling of α,β-unsaturated compounds with unactivated alkenes via cobalt-catalyzed vinylic C-H activation has been developed. The present catalytic reaction was examined with various differently functionalized unsaturated compounds and unactivated olefins. In these reactions, highly valuable amide functionalized butadienes and indenones were prepared in good to excellent yields. A possible reaction mechanism is proposed involving directed olefinic C-H activation through a base-assisted deprotonation pathway.