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Stereoselective synthesis of 1,2,2-trisubstituted indane derivatives using a tandem S<inf>N</inf>2-michael addition sequence
Date Issued
24-07-2007
Author(s)
Gharpure, Santosh J.
Reddy, S. Raja Bhushan
Sanyal, Udishnu
Abstract
An efficient strategy is developed for the synthesis of 1,2,2-trisubstituted indane derivatives employing a tandem SN2- Michael reaction sequence. The method is extended towards the synthesis of spiroindanes and indanopiperidines. © Georg Thieme Verlag Stuttgart.