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Determination of isoniazid in pharmaceutical preparations by reaction with radiochloramine-B

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cris.author.scopus-author-id7801558651
cris.author.scopus-author-id58407589500
cris.author.scopus-author-id16146848300
dc.contributor.authorSubhashini, M.
dc.contributor.authorSubramanian, M. S.
dc.contributor.authorRao, V. R.S.
dc.date.accessioned2023-09-20T06:46:15Z
dc.date.available2023-09-20T06:46:15Z
dc.date.issued01-01-1989
dc.description.abstractA method has been developed for the determination of isoniazid (INH) at microgram level in pharmaceutical preparations based on the oxidation of isoniazid by radiochloramine-B. Interference of vitamin C has been overcome by precipitation as lead ascorbate and that of rifampicin and p-aminosalicylic acid by selective extraction. Amounts as low as 25 μg of INH can be determined. © 1990.
dc.identifier.doi10.1016/0731-7085(89)80153-0
dc.identifier.issn7317085
dc.identifier.pmid2490531
dc.identifier.scopus2-s2.0-0024806557
dc.identifier.urihttps://apicris.irins.org/handle/IITM2023/60873
dc.relation.ispartofseriesJournal of Pharmaceutical and Biomedical Analysis
dc.sourceJournal of Pharmaceutical and Biomedical Analysis
dc.subjectactivity measurement
dc.subjectdrug analysis.
dc.subjectisoniazid
dc.subjectRadiochloramine-B
dc.titleDetermination of isoniazid in pharmaceutical preparations by reaction with radiochloramine-B
dc.typeJournal
dspace.entity.typePublication
oaire.citation.endPage1477
oaire.citation.issue12
oaire.citation.startPage1473
oaire.citation.volume7
person.affiliation.cityChennai
person.affiliation.id60025757
person.affiliation.nameIndian Institute of Technology Madras
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