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Alkylation, Annulation, and Alkenylation of Organic Molecules with Maleimides by Transition-Metal-Catalyzed C-H Bond Activation

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cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid0000-0002-7835-3928
cris.virtual.department#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.departmentIndian Institute of Technology, Madras
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid9c678988-de4d-424d-b069-9cd94c4bb30a
cris.virtualsource.department#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.department9c678988-de4d-424d-b069-9cd94c4bb30a
dc.contributor.authorManoharan, Ramasamy
dc.contributor.authorJeganmohan, Masilamani
dc.date.accessioned2023-09-19T13:40:07Z
dc.date.available2023-09-19T13:40:07Z
dc.date.issued01-11-2019
dc.description.abstractMaleimide and succinimide core moieties are present in various natural products and pharmaceuticals. In addition, these derivatives can be readily modified into biologically important organic molecules including pyrrolidines and γ-lactams. A transition-metal-catalyzed chelation-assisted functionalization of inert C−H bond of organic molecules with electrophiles or nucleophiles is one of the efficient methods to construct chemical bonds in a highly atom- and step-economical manner. The present review describes the recent advances in the reaction involving maleimides with organic molecules by a chelation-assisted inert C−H bond activation methodology. The reaction involving maleimides with organic molecules having directing groups, such as ketone, acyl, pyridyl, pyrimidyl, oxime, amide, imidate, chromone, azo, N-sulfonyl ketimine, carboxylic acids, and aldimines, were described. The scope, limitation and mechanistic investigation of the alkylation, annulation and alkenylation reactions were discussed elaborately. This review article includes the entire report on the chemical bond-forming reaction of maleimides with organic molecules by the C−H bond activation strategy until the end of 2018.
dc.identifier.doi10.1002/ajoc.201900054
dc.identifier.issn21935807
dc.identifier.scopus2-s2.0-85065670621
dc.identifier.urihttps://apicris.irins.org/handle/IITM2023/23006
dc.relation.ispartofseriesAsian Journal of Organic Chemistry
dc.sourceAsian Journal of Organic Chemistry
dc.subjectalkylation
dc.subjectannulation
dc.subjectC−H activation
dc.subjectmaleimide
dc.subjectsuccinimide
dc.titleAlkylation, Annulation, and Alkenylation of Organic Molecules with Maleimides by Transition-Metal-Catalyzed C-H Bond Activation
dc.typeJournal
dspace.entity.typePublication
oaire.citation.endPage1969
oaire.citation.issue11
oaire.citation.startPage1949
oaire.citation.volume8
oairecerif.author.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#
oairecerif.author.affiliationIndian Institute of Technology, Madras
person.affiliation.cityChennai
person.affiliation.id60025757
person.affiliation.nameIndian Institute of Technology Madras
person.identifier.scopus-author-id57210657949
person.identifier.scopus-author-id8515375100
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